Quercetin Dihydrate vs Quercetin Anhydrous, What's The Difference?

If you're an entrepreneur, formulator, or buyer in the supplement or skincare industries, you've likely come across Quercetin - a powerful antioxidant found in plants like the Sophora japonica tree. But did you know there are two main forms of Quercetin used in products? Understanding the difference between Quercetin Anhydrous (also called Quercetin Anhydrate) and Quercetin Dihydrate is crucial for selecting the right ingredient for your formulations.

What is Quercetin?

Before diving into the difference, let's quickly review what Quercetin is. Quercetin is a flavonoid compound renowned for its potent anti-inflammatory, antioxidant, and immune-boosting properties. It's found naturally in fruits, vegetables, grains, and herbs, but it's also widely available as a dietary supplement.

Quercetin Anhydrous: The Water-Free Form

Quercetin Anhydrous, also known as aglycone Quercetin, is the water-free form of Quercetin. It's a yellow crystalline powder that's highly concentrated and stable. This form is ideal for supplements and formulations that require a high potency of Quercetin without added water molecules.

Key features of Quercetin Anhydrous:

• Higher concentration of active Quercetin (98% or higher purity)

• Better stability and longer shelf life

• Suitable for capsules, tablets, and dry formulations

Quercetin Dihydrate: The Water-Containing Form

Quercetin Dihydrate, on the other hand, contains two molecules of water bound to each molecule of Quercetin. It's a yellow-brown powder that's less concentrated but more water-soluble than the anhydrous form.

Key features of Quercetin Dihydrate:

• Lower concentration of active Quercetin (typically around 80% purity)

• Better water solubility, making it suitable for liquid formulations

• Potentially more bioavailable due to improved solubility

Which Form is Right for Your Product?

The choice between Quercetin Anhydrous and Quercetin Dihydrate depends on your specific formulation needs and product format. Here are some general guidelines:

• For capsules, tablets, and dry formulations, Quercetin Anhydrous is often preferred due to its higher potency and stability.

• For liquid formulations like tinctures, syrups, or topical creams, Quercetin Dihydrate may be a better choice due to its improved water solubility.

• If you require a highly concentrated source of Quercetin, the anhydrous form is the way to go.

• If cost is a concern, Quercetin Dihydrate may be more economical, but you'll need to use a higher dosage to achieve the same potency.

• As a world-leading manufacturer of both Quercetin Anhydrous and Quercetin Dihydrate derived from the Sophora japonica tree, we can provide high-quality ingredients tailored to your specific needs. Our team of experts can guide you in selecting the right form and concentration for your products, ensuring optimal efficacy and stability.

Don't compromise on quality when it comes to Quercetin. Contact us today to discuss your formulation requirements and take advantage of our expertise in this powerful antioxidant. We are the world-leader in Quercetin and Sophora Japonica extracts, trust us with your project and business.

Our Quercetin is used by some of the biggest brands in the world, and are known for the reliable quality. What's more, we can customize specs to your specific product vision.

References:

1. Li, Y., Yao, J., Han, C., Yang, J., Chaudhry, M. T., Wang, S., ... & Yin, Y. (2016). Quercetin, inflammation and immunity. Nutrients, 8(3), 167.

2. Anhe, G. F., Varin, T. V., Le Barz, M., Desjardins, Y., Levy, E., Roy, D., & Marette, A. (2018). Gut microbial dysbiosis in obesity-linked metabolic diseases and prebiotic potential of polyphenol-rich extracts. Nutrients, 10(8), 1033.

3. Russo, M., Spagnuolo, C., Tedesco, I., Bilotto, S., & Russo, G. L. (2012). The flavonoid Quercetin in disease prevention and therapy. Antioxidants, 1(1), 3-35.

4. Boots, A. W., Haenen, G. R., & Bast, A. (2008). Health effects of Quercetin: from antioxidant to nutraceutical. European journal of pharmacology, 585(2-3), 325-337.

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